Researchers with UMKC’s School of Pharmacy have developed a new method called a photoactivated depot to make insulin administration easier and more effective. They wrote about the advance for an upcoming issue of Angewandte Chemie, the highest ranked weekly chemistry journal in the world. The article is titled “A Photoactivated Insulin Depot.”
With a photoactivated depot (PAD), insulin is linked to an insoluble polymer by a connection that can be broken with light. The depot can be injected just under the patient’s skin. Insulin can then be released from the polymer by light irradiation through the skin, and then absorbed into the body. Since one injected depot can contain a large amount of insulin, the PAD has the potential to eliminate hundreds of injections. In addition, because light can be administered at any time interval, the release of insulin could be more finely controlled.
Simon Friedman, associate professor of pharmacy and his student co-authors, Piyush Jain and Dipu Karunakaran, successfully made the first generation of PAD’s.
For additional information, visit UMKC Today; media coverage on the research is listed below.
UMKC find could replace insulin needles with light beams (School of Pharmacy) – Kansas City Star
UMKC Researchers Find New Way of Administering Insulin (School of Pharmacy) – KMOX Radio (St. Louis)